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Explore our research contributions in cell membrane repair, cancer biology, regenerative medicine, and therapeutic protein development.

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20237 citations

MG53 mitigates nitrogen mustard-induced skin injury

Authors: H Li, Z Li, X Li, C Cai, SL Zhao, RE Merritt, X Zhou, T Tan, V Bergdall, ...

Journal: Cells

DOI: 10.3390/cells12141915

202236 citations

Sustained delivery of rhMG53 promotes diabetic wound healing and hair follicle development

Authors: H Niu, H Li, Y Guan, X Zhou, Z Li, SL Zhao, P Chen, T Tan, H Zhu, ...

Journal: Bioactive Materials

DOI: 10.1016/j.bioactmat.2022.03.017

202230 citations

The cell membrane repair protein MG53 modulates transcription factor NF-κB signaling to control kidney fibrosis

Authors: H Li, P Duann, Z Li, X Zhou, J Ma, BH Rovin, PH Lin

Journal: Kidney International

DOI: 10.1016/j.kint.2021.09.027

202211 citations

MG53 attenuates nitrogen mustard‐induced acute lung injury

Authors: H Li, L Rosas, Z Li, Z Bian, X Li, K Choi, C Cai, X Zhou, T Tan, V Bergdall, ...

Journal: Journal of Cellular and Molecular Medicine

DOI: 10.1111/jcmm.16917

202210 citations

MG53 inhibits cellular proliferation and tumor progression in colorectal carcinoma

Authors: P Gupta, H Li, GN Zhang, AM Barbuti, Y Yang, P Lin, C Cai, T Tan, J Ma, ...

Journal: International Journal of Biological Sciences

DOI: 10.7150/ijbs.67869

20220 citations

New Modalities in Cancer Diagnostics and Therapeutics

Authors: L Zhao, DH Yang, H Li

Journal: Frontiers in Pharmacology

DOI: 10.3389/fphar.2022.1101506

20220 citations

New Modalities in Cancer Diagnostics and Therapeutics (E-book)

Authors: DH Yang, H Li

Journal: Frontiers in Pharmacology

DOI: 10.3389/978-2-83251-045-2

202164 citations

MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer

Authors: H Li, PH Lin, P Gupta, X Li, SL Zhao, X Zhou, Z Li, S Wei, L Xu, R Han, ...

Journal: Molecular Cancer

DOI: 10.1186/s12943-021-01418-3

202127 citations

Recombinant MG53 protein protects mice from lethal influenza virus infection

Authors: AD Kenney, Z Li, Z Bian, X Zhou, H Li, BA Whitson, T Tan, C Cai, J Ma, ...

Journal: American Journal of Respiratory and Critical Care Medicine

DOI: 10.1164/rccm.202007-2908LE

202118 citations

MG53 as a novel therapeutic protein to treat acute lung injury

Authors: BA Whitson, K Mulier, H Li, X Zhou, C Cai, SM Black, T Tan, J Ma, ...

Journal: Military Medicine

DOI: 10.1093/milmed/usaa313

20210 citations

New Technologies in Cancer Diagnostics and Therapeutics

Authors: H Li, L Zhao, P Cohen, DH Yang

Journal: Frontiers in Pharmacology

DOI: 10.3389/fphar.2021.760833

20210 citations

New Technologies in Cancer Diagnostics and Therapeutics (E-book)

Authors: DH Yang, P Cohen, H Li, Y Yu

Journal: Frontiers in Pharmacology

DOI: 10.3389/978-2-88971-524-4

202054 citations

MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

Authors: M Sermersheim, AD Kenney, PH Lin, TM McMichael, C Cai, K Gumpper, ...

Journal: Nature Communications

DOI: 10.1038/s41467-020-17177-6

202046 citations

MG53 Does Not Manifest the Development of Diabetes in db/db Mice

Authors: Q Wang, Z Bian, Q Jiang, X Wang, X Zhou, KH Park, W Hsueh, ...

Journal: Diabetes

DOI: 10.2337/db19-0807

202027 citations

MG53 protects against contrast-induced acute kidney injury by reducing cell membrane damage and apoptosis

Authors: C Liu, Y Hu, Y Han, Y Wang, Y Zhang, X Zhang, D He, H Ren, Y Liu, ...

Journal: Acta Pharmacologica Sinica

DOI: 10.1038/s41401-020-0420-8

201971 citations

Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function

Authors: Z Bian, Q Wang, X Zhou, T Tan, KH Park, HF Kramer, A McDougal, ...

Journal: Nature Communications

DOI: 10.1038/s41467-019-12483-0

201966 citations

Spatiotemporal delivery of basic fibroblast growth factor to directly and simultaneously attenuate cardiac fibrosis and promote cardiac tissue vascularization following myocardial infarction

Authors: Z Fan, Z Xu, H Niu, Y Sui, H Li, J Ma, J Guan

Journal: Journal of Controlled Release

DOI: 10.1016/j.jconrel.2019.09.005

201962 citations

mTORC1 mediates lysine-induced satellite cell activation to promote skeletal muscle growth

Authors: C Jin, J Ye, J Yang, C Gao, H Yan, H Li, X Wang

Journal: Cells

DOI: 10.3390/cells8121549

201949 citations

Thermosensitive, fast gelling, photoluminescent, highly flexible, and degradable hydrogels for stem cell delivery

Authors: H Niu, X Li, H Li, Z Fan, J Ma, J Guan

Journal: Acta Biomaterialia

DOI: 10.1016/j.actbio.2018.10.038

201917 citations

Lysine-induced swine satellite cell migration is mediated by the FAK pathway

Authors: C Jin, Z Zhang, J Ye, C Gao, H Yan, H Li, J Yang, X Wang

Journal: Food & Function

DOI: 10.1039/C8FO02066C

2018141 citations

An injectable oxygen release system to augment cell survival and promote cardiac repair following myocardial infarction

Authors: Z Fan, Z Xu, H Niu, N Gao, Y Guan, C Li, Y Dang, X Cui, XL Liu, Y Duan, ...

Journal: Scientific Reports

DOI: 10.1038/s41598-018-19906-w

201842 citations

Effects of pioglitazone hydrochloride and vitamin E on meat quality, antioxidant status and fatty acid profiles in finishing pigs

Authors: C Jin, C Gao, Q Wang, Z Zhang, Y Xu, H Li, H Yan, X Wang

Journal: Meat Science

DOI: 10.1016/j.meatsci.2018.07.008

201833 citations

Dietary supplementation with pioglitazone hydrochloride and chromium methionine improves growth performance, meat quality, and antioxidant ability in finishing pigs

Authors: C Jin, Q Wang, Z Zhang, Y Xu, H Yan, H Li, C Gao, X Wang

Journal: Journal of Agricultural and Food Chemistry

DOI: 10.1021/acs.jafc.8b01176

2017689 citations

Zinc in wound healing modulation

Authors: PH Lin, M Sermersheim, H Li, PHU Lee, SM Steinberg, J Ma

Journal: Nutrients

DOI: 10.3390/nu10010016

2017178 citations

A bioinspired alginate-gum arabic hydrogel with micro-/nanoscale structures for controlled drug release in chronic wound healing

Authors: M Li, H Li, X Li, H Zhu, Z Xu, L Liu, J Ma, M Zhang

Journal: ACS Applied Materials & Interfaces

DOI: 10.1021/acsami.7b04428

201798 citations

Sustained release of a peptide-based matrix metalloproteinase-2 inhibitor to attenuate adverse cardiac remodeling and improve cardiac function following myocardial infarction

Authors: Z Fan, M Fu, Z Xu, B Zhang, Z Li, H Li, X Zhou, X Liu, Y Duan, PH Lin, ...

Journal: Biomacromolecules

DOI: 10.1021/acs.biomac.7b00760

20179 citations

Differentiation capacities of skeletal muscle satellite cells in Lantang and Landrace piglets

Authors: CQ Gao, YL Xu, CL Jin, XC Hu, HC Li, GX Xing, HC Yan, XQ Wang

Journal: Oncotarget

DOI: 10.18632/oncotarget.17860

201671 citations

MG53 permeates through blood-brain barrier to protect ischemic brain injury

Authors: Y Yao, B Zhang, H Zhu, H Li, Y Han, K Chen, Z Wang, J Zeng, Y Liu, ...

Journal: Oncotarget

DOI: 10.18632/oncotarget.22474

201637 citations

Focal adhesion kinase and paxillin promote migration and adhesion to fibronectin by swine skeletal muscle satellite cells

Authors: D Wang, C Gao, R Chen, C Jin, H Li, H Yan, X Wang

Journal: Oncotarget

DOI: 10.18632/oncotarget.9010

201632 citations

L-Glutamate deficiency can trigger proliferation inhibition via down regulation of the mTOR/S6K1 pathway in pig intestinal epithelial cells

Authors: XG Li, WG Sui, CQ Gao, HC Yan, YL Yin, HC Li, XQ Wang

Journal: Journal of Animal Science

DOI: 10.2527/jas.2015-9432

20165 citations

Satellite cells isolated from skeletal muscle will proliferate faster in WENS yellow feather chicks

Authors: CQ Gao, HJ Zhang, HC Yan, L Yuan, S Dahanayaka, HC Li, XQ Wang

Journal: Animal Science Journal

DOI: 10.1111/asj.12403

2015154 citations

MG53-mediated cell membrane repair protects against acute kidney injury

Authors: P Duann, H Li, P Lin, T Tan, Z Wang, K Chen, X Zhou, K Gumpper, H Zhu, ...

Journal: Science Translational Medicine

DOI: 10.1126/scitranslmed.3010755

2015109 citations

Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling

Authors: PH Lin, P Duann, S Komazaki, KH Park, H Li, M Sun, M Sermersheim, ...

Journal: Journal of Biological Chemistry

DOI: 10.1074/jbc.M114.608471

201594 citations

Modulation of wound healing and scar formation by MG53 protein-mediated cell membrane repair

Authors: H Li, P Duann, PH Lin, L Zhao, Z Fan, T Tan, X Zhou, M Sun, M Fu, ...

Journal: Journal of Biological Chemistry

DOI: 10.1074/jbc.M115.680074

201561 citations

Heat stress inhibits proliferation, promotes growth, and induces apoptosis in cultured Lantang swine skeletal muscle satellite cells

Authors: C Gao, Y Zhao, H Li, W Sui, H Yan, X Wang

Journal: Journal of Zhejiang University-SCIENCE B

DOI: 10.1631/jzus.B1400339

201521 citations

Low dose of IGF‐I increases cell size of skeletal muscle satellite cells via Akt/S6K signaling pathway

Authors: C Gao, R Zhi, Z Yang, H Li, H Yan, X Wang

Journal: Journal of Cellular Biochemistry

DOI: 10.1002/jcb.25212

2014145 citations

Treatment of acute lung injury by targeting MG53-mediated cell membrane repair

Authors: Y Jia, K Chen, P Lin, G Lieber, M Nishi, R Yan, Z Wang, Y Yao, Y Li, ...

Journal: Nature Communications

DOI: 10.1038/ncomms5387

201430 citations

Amphipathic tail-anchoring peptide is a promising therapeutic agent for prostate cancer treatment

Authors: G De, JK Ko, T Tan, H Zhu, H Li, J Ma

Journal: Oncotarget

DOI: 10.18632/oncotarget.2301

201418 citations

Immobilization of insulin-like growth factor-1 onto thermosensitive hydrogels to enhance cardiac progenitor cell survival and differentiation under ischemic conditions

Authors: ZQ Li, YY Xu, HC Li, JJ Guan

Journal: Science China Chemistry

DOI: 10.1007/s11426-014-5089-8

20145 citations

The therapeutic role of recombinant human MG53 protein in wound healing

Authors: H Li, P Duann, Z Fan, L Zhao, PH Lin, M Sun, G De, X Zhou, J Guan, J Ma

Journal: Biophysical Journal

DOI: 10.1016/j.bpj.2013.11.594

201342 citations

Experimental evidence for UNC-6 (netrin) axon guidance by stochastic fluctuations of intracellular UNC-40 (DCC) outgrowth activity

Authors: G Kulkarni, Z Xu, AM Mohamed, H Li, X Tang, G Limerick, WG Wadsworth

Journal: Biology Open

DOI: 10.1242/bio.20136346

200932 citations

The roles of multiple UNC-40 (DCC) receptor-mediated signals in determining neuronal asymmetry induced by the UNC-6 (netrin) ligand

Authors: Z Xu, H Li, WG Wadsworth

Journal: Genetics

DOI: 10.1534/genetics.109.108654

200872 citations

RPM-1, a Caenorhabditis elegans protein that functions in presynaptic differentiation, negatively regulates axon outgrowth by controlling SAX-3/robo and UNC-5/UNC5 activity

Authors: H Li, G Kulkarni, WG Wadsworth

Journal: Journal of Neuroscience

DOI: 10.1523/JNEUROSCI.5536-07.2008

200835 citations

CLEC-38, a transmembrane protein with C-type lectin-like domains, negatively regulates UNC-40-mediated axon outgrowth and promotes presynaptic development in Caenorhabditis elegans

Authors: G Kulkarni, H Li, WG Wadsworth

Journal: Journal of Neuroscience

DOI: 10.1523/JNEUROSCI.5542-07.2008

2005265 citations

Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways

Authors: M Yamaguchi, N Tonou-Fujimori, A Komori, R Maeda, Y Nojima, H Li, ...

Journal: Development

DOI: 10.1242/dev.01881

200138 citations

Restriction of proliferation of primordial germ cells by the irradiation of Japanese quail embryos with soft X-rays

Authors: HC Li, H Kagami, K Matsui, T Ono

Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

DOI: 10.1016/s1095-6433(01)00375-0

200117 citations

Identification of transferred chicken germ cells in quail gonad and semen by amplification of chicken-specific PCR products

Authors: HC Li, L Zhao, H Kagami, K Matsui, T Ono

Journal: The Journal of Poultry Science

DOI: 10.2141/jpsa.38.308

200111 citations

Population of circulating primordial germ cells in early Japanese quail embryos

Authors: HC Li, K Matsui, T Ono

Journal: The Journal of Poultry Science

DOI: 10.2141/jpsa.38.175

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