1900 Coffey Road, Columbus, OH 43210
614-247-5703
li.3714@osu.edu

Research Overview

Our laboratory focuses on advancing regenerative medicine through cutting-edge research in cell membrane repair mechanisms, cancer biology, and therapeutic protein development. We bridge the gap between basic molecular science and clinical applications, with the ultimate goal of developing novel therapeutic strategies for treating various diseases and injuries.

"Advancing regenerative medicine through research in cell membrane repair, cancer biology, and therapeutic protein development."

Research Projects

MG53 Protein in Cell Membrane Repair

active

Investigating the role of MG53 protein in cell membrane repair mechanisms and its therapeutic potential for treating various diseases including diabetes, cardiovascular disease, and acute lung injury.

Key Findings:

  • MG53 protects against acute kidney injury
  • Promotes wound healing and tissue regeneration
  • Enhances cell survival under stress conditions

Collaborators: Dr. Jane Smith, Dr. John Doe

Funding: NIH R01 Grant

Cancer Biology & Tumor Suppressors

active

Research on tumor suppressors in lung cancer and other solid tumors, with focus on drug resistance mechanisms and MG53's role in suppressing tumor progression.

Key Findings:

  • MG53 suppresses tumor progression in non-small cell lung cancer
  • Reduces stress granule formation in cancer cells
  • Opens new therapeutic avenues for cancer treatment

Collaborators: Dr. Sarah Johnson

Funding: American Cancer Society

Regenerative Medicine & Bioinspired Hydrogels

active

Development of innovative approaches to tissue repair and regeneration, including bioinspired hydrogels for controlled drug release and sustained delivery systems for therapeutic proteins.

Key Findings:

  • Bioinspired hydrogels for controlled drug release
  • Sustained delivery systems for therapeutic proteins
  • Promising results for chronic wound treatment in diabetic patients

Collaborators: Dr. Michael Chen, Dr. Lisa Wang

Funding: NSF Grant

Translational Medicine & Protein Therapy

active

Bridging basic science and clinical applications, with several therapeutic proteins and delivery systems moving toward clinical translation.

Key Findings:

  • Recombinant human MG53 protein shows protective effects
  • Protection against influenza virus infection
  • Demonstrates translational potential for tissue injury treatment

Collaborators: Dr. Robert Kim, Dr. Maria Garcia

Funding: Industry Partnership

Research Impact

3,096
Total Citations
30
H-Index
48+
Publications